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Commission Implementing Regulation (EU) 2021/808 of 22 March 2021 concerning the performance of analytical methods for residues of pharmacologically active substances used in food-producing animals and the interpretation of results, and methods to be used for sampling, and repealing Decisions 2002/657/EC and 98/179/EC.

Regulation (EU) 2017/625 lays down rules for the performance of official controls and other official activities by the competent authorities of the Member States to verify compliance with Union legislation, inter alia, in the area of food safety at all stages of the production, processing and distribution process. It lays down specific rules on official controls concerning substances whose use may generate residues in food and feed, as well as general requirements for the methods to be used for sampling, analysis and laboratory testing during official controls and other official activities.

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Robotic process automation (RPA) offers increased speed and efficiency, the flexibility to cope with peak demand or delays, and the reduction of manually entered errors. Some governments are already using a virtual workforce to automate routine business processes, easing the burden of repetitive, high-volume tasks and freeing up time and resources that can be focused on front-line services.

Governments have a responsibility to protect their citizens from a range of threats, enabling them to live and work without fear. Digitization is both a hindrance and a help in this fight.

On the other hand, digital technologies and improved data sharing provide a sophisticated means of combating threats. Defense organizations are investing in artificial intelligence and machine learning; threat detection programs and cyber weapons; cybersecurity apparatus; Robotics and digital tools to make them more agile and effective. Police forces are using mobile technologies to reduce incident response times, while data analytics enables predictive policing models and better threat analysis planning.

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As a result, in April 2011 Namecoin was born. A spin-off project from Bitcoin that had a goal beyond creating another cryptocurrency. Namecoin was conceived with the aim of creating a domain name service (DNS) based on blockchain. The outcome of the project was a success. This led to the release of the source code and the subsequent improvement and evolution of the source code. This has allowed Namecoin to have an active community. It has also demonstrated that blockchain technology has the capacity to address different use cases and evolve beyond economic systems.

After the release of Bitcoin in 2008, Satoshi Nakamoto and Gavin Andresen proposed transforming Bitcoin into an effective domain name service or DNS. This proposal was initially called BitDNS. With it they seek to create a completely decentralized and secure DNS system.

The first proposal for the construction of this system came from the Bitcointalk forum user appamatto. He first spoke about a decentralized DNS system on November 15, 2010. At that time, appamatto laid the first real theoretical foundations of this new system. At that point, his idea mainly wanted to address the problem of “authority” or centralized control.

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Currently, the dissemination of carbapenemase-producing Enterobacteriaceae is considered a serious clinical problem due to the failure to treat the infections they cause. Among the carbapenemases, the KPC enzyme has been disseminated worldwide and has been identified in the main species of enterobacteria associated with healthcare-associated infections, with a clear predominance of Klebsiella pneumoniae worldwide. The blaKPC gene is mainly carried by the Tn4401 transposon, detected in several species of enterobacteria with different sequencing-types (ST) and different geographic origin. Additionally, new genetic platforms have been described that are distinguished from the original Tn4401 due to insertions and deletions of other genes. Plasmids harboring the blaKPC gene can be of the conjugative and non-conjugative mobilizable type, and also contain other genetic determinants of resistance. KPC-producing strains can exhibit varying levels of resistance to carbapenemics, due to the involvement of additional mechanisms such as different degree of expression of porins and efflux pumps associated with the production of extended-spectrum β-lactamases and/or AmpC. However, carbapenemases, with KPC as the most frequent enzyme, confer higher degrees of resistance.